FPWR Research Scientific Review Criteria

Scientific reviewers will be selected based on competence as a scientific investigator, scientific achievements and honors, and expertise in the area of the proposed research. The scientific reviewers will evaluate the scientific merit of the proposed research using the criteria listed below, evaluate the appropriateness of the budget, and review animal and human subject use.

Scientific Peer Review Evaluation Criteria

Significance and Relevance:
Does the proposed study address a critical problem in the field of Prader-Willi syndrome research? How will the successful completion of the proposed studies advance our understanding of Prader-Willi syndrome and lead to the goal of developing effective therapies to treat PWS? What will be the effect of these studies on the concepts or methods in the field of PWS and related research?

Innovation:
Are the aims of the study innovative and original? Do the proposed studies use novel concepts, approaches or methods? Does the project challenge existing paradigms, develop new methodologies, or explore new or understudied areas?

Research Strategy:
Are the experimental design, methods, and data analysis logical, well designed, well developed and integrated? Will the proposed studies appropriately address the experimental problem? Is sound scientific reasoning apparent? Is there supportive preliminary data when necessary? Are potential problems anticipated and alternatives proposed? Are the proposed studies feasible?

Principal Investigator:
Is the principal investigator appropriately trained to carry out the proposed research? Has the PI included collaborators with expertise needed to conduct the research successfully? Are the necessary collaborative arrangements in place?

Overall Evaluation:
Briefly summarize the major strengths and weaknesses of the application in terms of the review criteria, emphasizing those areas you feel are most relevant for the application.